After Moving of Regulatory T-Cell Therapy to the Clinic: Will We Need a New Tregs Source?
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چکیده
Submit Manuscript | http://medcraveonline.com Abbreviations: AMP: Adenosine Monophosphate; ATP: Adenosine Triphosphate; cAMP: Cyclic Adenosine Monophosphate; CD: Cluster of Differentiation; CTLA-4: Cytotoxic T-LymphocyteAssociated Protein 4; IDO: Indoleamine 2,3-dioxygenase; IFN: Interferon; IL: Interleukin; LAG3: Lymphocyte-Activation Gene 3; TCR: T Cell Receptor; TGF-β: Transforming Growth Factor-Β; Th: T Helper Cell; HSCT: Hematopoietic Stem Cell Transplantation; Tregs: Regulatory T cells; iPSCs: Induced Pluripotent Stem Cells; SOT: Solid Organ Transplantation; NKT: Natural Killer T; TNF: Tumour-Necrosis Factor; CTLA4: Cytotoxic T-Lymphocyte Antigen 4; FOXP3: Forkhead Box P3; AA: Aplastic Anemia; SLE: Systemic Lupus Erythematosus; T1D: Type 1 Diabetes; DCs: Dendritic Cells; PB: Peripheral Blood; UCB: Umbilical Cord Blood; FACS: Fluorescence Activated Cell Sorting; TSDR: Treg-Specific Demethylated Region; CAR: Chimeric Antigen Receptors; EAE: Experimental Autoimmune Encephalitis; ES: Embryonic Stem; ATG: Anti-Thymocyte Globulin
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